AQP3 is regulated by PPARγ and JNK in hepatic stellate cells carrying PNPLA3 I148M

Aquaglyceroporins (AQPs) allow the movement of glycerol that is required for triglyceride formation in hepatic stellate cells (HSC), as key cellular source of fibrogenesis in the liver. The genetic polymorphism I148M of the patatin-like phospholipase domain-containing 3 (PNPLA3) is associated with h...

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Foilsithe in:Sci Rep
Main Authors: Tardelli, Matteo, Bruschi, Francesca V., Claudel, Thierry, Moreno-Viedma, Veronica, Halilbasic, Emina, Marra, Fabio, Herac, Merima, Stulnig, Thomas M., Trauner, Michael
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2017
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676689/
https://ncbi.nlm.nih.gov/pubmed/29116096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14557-9
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