Mitochondrial-Based Therapeutics for the Treatment of Spinal Cord Injury: Mitochondrial Biogenesis as a Potential Pharmacological Target

Spinal cord injury (SCI) is characterized by an initial trauma followed by a progressive cascade of damage referred to as secondary injury. A hallmark of secondary injury is vascular disruption leading to vasoconstriction and decreased oxygen delivery, which directly reduces the ability of mitochond...

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Publicat a:J Pharmacol Exp Ther
Autors principals: Scholpa, Natalie E., Schnellmann, Rick G.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676296/
https://ncbi.nlm.nih.gov/pubmed/28935700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.117.244806
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