5‐HT(1F) receptor‐mediated mitochondrial biogenesis for the treatment of Parkinson's disease

BACKGROUND AND PURPOSE: Parkinson's disease is characterized by progressive decline in motor function due to degeneration of nigrostriatal dopaminergic neurons, as well as other deficits including cognitive impairment and behavioural abnormalities. Mitochondrial dysfunction, leading to loss of...

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Vydáno v:Br J Pharmacol
Hlavní autoři: Scholpa, Natalie E, Lynn, Mary K, Corum, Daniel, Boger, Heather A, Schnellmann, Rick G
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758398/
https://ncbi.nlm.nih.gov/pubmed/29057453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14076
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