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β(2)-adrenergic receptor-mediated mitochondrial biogenesis improves skeletal muscle recovery following spinal cord injury

In addition to local spinal cord dysfunction, spinal cord injury (SCI) can result in decreased skeletal muscle mitochondrial activity and muscle atrophy. Treatment with the FDA-approved β(2)-adrenergic receptor (ADRB2) agonist formoterol has been shown to induce mitochondrial biogenesis (MB) in both...

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Bibliographic Details
Published in:Exp Neurol
Main Authors: Scholpa, Natalie E., Simmons, Epiphani C., Tilley, Douglas G., Schnellmann, Rick G.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7751764/
https://ncbi.nlm.nih.gov/pubmed/31525347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2019.113064
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