Rapid, Selection-Free, High-Efficiency Genome Editing in Protozoan Parasites Using CRISPR-Cas9 Ribonucleoproteins

Trypanosomatids (order Kinetoplastida), including the human pathogens Trypanosoma cruzi (agent of Chagas disease), Trypanosoma brucei, (African sleeping sickness), and Leishmania (leishmaniasis), affect millions of people and animals globally. T. cruzi is considered one of the least studied and most...

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Dades bibliogràfiques
Publicat a:mBio
Autors principals: Soares Medeiros, Lia Carolina, South, Lilith, Peng, Duo, Bustamante, Juan M., Wang, Wei, Bunkofske, Molly, Perumal, Natasha, Sanchez-Valdez, Fernando, Tarleton, Rick L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676044/
https://ncbi.nlm.nih.gov/pubmed/29114029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01788-17
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