Rapid, Selection-Free, High-Efficiency Genome Editing in Protozoan Parasites Using CRISPR-Cas9 Ribonucleoproteins

Trypanosomatids (order Kinetoplastida), including the human pathogens Trypanosoma cruzi (agent of Chagas disease), Trypanosoma brucei, (African sleeping sickness), and Leishmania (leishmaniasis), affect millions of people and animals globally. T. cruzi is considered one of the least studied and most...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Soares Medeiros, Lia Carolina, South, Lilith, Peng, Duo, Bustamante, Juan M., Wang, Wei, Bunkofske, Molly, Perumal, Natasha, Sanchez-Valdez, Fernando, Tarleton, Rick L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676044/
https://ncbi.nlm.nih.gov/pubmed/29114029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01788-17
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