Glutaredoxin-2 controls cardiac mitochondrial dynamics and energetics in mice, and protects against human cardiac pathologies

Glutaredoxin 2 (GRX2), a mitochondrial glutathione-dependent oxidoreductase, is central to glutathione homeostasis and mitochondrial redox, which is crucial in highly metabolic tissues like the heart. Previous research showed that absence of Grx2, leads to impaired mitochondrial complex I function,...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Kanaan, Georges N., Ichim, Bianca, Gharibeh, Lara, Maharsy, Wael, Patten, David A., Xuan, Jian Ying, Reunov, Arkadiy, Marshall, Philip, Veinot, John, Menzies, Keir, Nemer, Mona, Harper, Mary-Ellen
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675898/
https://ncbi.nlm.nih.gov/pubmed/29101900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.10.019
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