Efficacy and Safety of Spironolactone in Acute Heart Failure: The ATHENA-HF Randomized Clinical Trial

IMPORTANCE: Persistent congestion is associated with worse outcomes in acute heart failure (AHF). Mineralocorticoid receptor antagonists administered at high doses may relieve congestion, overcome diuretic resistance, and mitigate the effects of adverse neurohormonal activation in AHF. OBJECTIVE: To...

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Dades bibliogràfiques
Publicat a:JAMA Cardiol
Autors principals: Butler, Javed, Anstrom, Kevin J., Felker, G. Michael, Givertz, Michael M., Kalogeropoulos, Andreas P., Konstam, Marvin A., Mann, Douglas L., Margulies, Kenneth B., McNulty, Steven E., Mentz, Robert J., Redfield, Margaret M., Tang, W. H. Wilson, Whellan, David J., Shah, Monica, Desvigne-Nickens, Patrice, Hernandez, Adrian F., Braunwald, Eugene
Format: Artigo
Idioma:Inglês
Publicat: American Medical Association 2017
Matèries:
Original Investigation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675712/
https://ncbi.nlm.nih.gov/pubmed/28700781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamacardio.2017.2198
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