Efficacy and Safety of Spironolactone in Acute Heart Failure: The ATHENA-HF Randomized Clinical Trial

IMPORTANCE: Persistent congestion is associated with worse outcomes in acute heart failure (AHF). Mineralocorticoid receptor antagonists administered at high doses may relieve congestion, overcome diuretic resistance, and mitigate the effects of adverse neurohormonal activation in AHF. OBJECTIVE: To...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:JAMA Cardiol
Main Authors: Butler, Javed, Anstrom, Kevin J., Felker, G. Michael, Givertz, Michael M., Kalogeropoulos, Andreas P., Konstam, Marvin A., Mann, Douglas L., Margulies, Kenneth B., McNulty, Steven E., Mentz, Robert J., Redfield, Margaret M., Tang, W. H. Wilson, Whellan, David J., Shah, Monica, Desvigne-Nickens, Patrice, Hernandez, Adrian F., Braunwald, Eugene
Format: Artigo
Jezik:Inglês
Izdano: American Medical Association 2017
Teme:
Original Investigation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675712/
https://ncbi.nlm.nih.gov/pubmed/28700781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamacardio.2017.2198
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