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Tissue-type plasminogen activator modulates macrophage M2 to M1 phenotypic change through annexin A2-mediated NF-κB pathway

Macrophage accumulation is one of the hallmarks of progressive kidney disease. In response to injury, macrophages undergo a phenotypic polarization to become two functionally distinct subsets: M1 and M2 macrophages. Macrophage polarization is a dynamic process, and recent work indicates that macroph...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lin, Ling, Hu, Kebin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675696/
https://ncbi.nlm.nih.gov/pubmed/29152144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21510
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