The non-canonical ubiquitin activating enzyme UBA6 suppresses epithelial-mesenchymal transition of mammary epithelial cells

Ubiquitination plays critical roles in the regulation of oncoproteins and tumor suppressors during carcinogenesis. The two ubiquitin activating enzymes (E1) in human genome, UBA1 and UBA6, initiate ubiquitination by ATP-dependent activation of ubiquitin. Recent evidence suggests that UBA1 and UBA6 p...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Liu, Xianpeng, Sun, Limin, Gursel, Demirkan B., Cheng, Chonghui, Huang, Sui, Rademaker, Alfred W., Khan, Seema A., Yin, Jun, Kiyokawa, Hiroaki
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675648/
https://ncbi.nlm.nih.gov/pubmed/29152096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20900
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