The non-canonical ubiquitin activating enzyme UBA6 suppresses epithelial-mesenchymal transition of mammary epithelial cells

Ubiquitination plays critical roles in the regulation of oncoproteins and tumor suppressors during carcinogenesis. The two ubiquitin activating enzymes (E1) in human genome, UBA1 and UBA6, initiate ubiquitination by ATP-dependent activation of ubiquitin. Recent evidence suggests that UBA1 and UBA6 p...

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Vydáno v:Oncotarget
Hlavní autoři: Liu, Xianpeng, Sun, Limin, Gursel, Demirkan B., Cheng, Chonghui, Huang, Sui, Rademaker, Alfred W., Khan, Seema A., Yin, Jun, Kiyokawa, Hiroaki
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675648/
https://ncbi.nlm.nih.gov/pubmed/29152096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20900
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