High glucose downregulates myocardin expression in rat glomerular mesangial cells via the ERK signaling pathway

Mesangial cells (MCs), which are vascular smooth muscle-derived cells, occupy the central position in the glomerulus. Diabetic nephropathy (DN) is one of the most common diabetes complications and is likely attributed to the loss of MC contractility. Myocardin stimulates downstream vascular smooth m...

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Опубликовано в: :Oncotarget
Главные авторы: Li, Ming, Xu, Lijuan, Feng, Guowei, Zhang, Yan, Wang, Xin, Wang, Yuebing
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2017
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Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675641/
https://ncbi.nlm.nih.gov/pubmed/29152089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20498
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