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SND p102 promotes extracellular matrix accumulation and cell proliferation in rat glomerular mesangial cells via the AT1R/ERK/Smad3 pathway

SND p102 was first described as a transcriptional co-activator, and subsequently determined to be a co-regulator of Pim-1, STAT6 and STAT5. We previously reported that SND p102 expression was increased in high glucose-treated mesangial cells (MCs) and plays a role in the extracellular matrix (ECM) a...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Xu, Jin-lan, Gan, Xin-xin, Ni, Jun, Shao, De-cui, Shen, Yang, Miao, Nai-jun, Xu, Dan, Zhou, Li, Zhang, Wei, Lu, Li-min
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289350/
https://ncbi.nlm.nih.gov/pubmed/30150789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.184
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