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High glucose downregulates myocardin expression in rat glomerular mesangial cells via the ERK signaling pathway

Mesangial cells (MCs), which are vascular smooth muscle-derived cells, occupy the central position in the glomerulus. Diabetic nephropathy (DN) is one of the most common diabetes complications and is likely attributed to the loss of MC contractility. Myocardin stimulates downstream vascular smooth m...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Li, Ming, Xu, Lijuan, Feng, Guowei, Zhang, Yan, Wang, Xin, Wang, Yuebing
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675641/
https://ncbi.nlm.nih.gov/pubmed/29152089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20498
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