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Bioorthogonal Labeling of Human Prostate Cancer Tissue Slice Cultures for Glycoproteomics

Sialylated glycans are found at elevated levels in many types of cancer and have been implicated in disease progression. However, the specific glycoproteins that contribute to the cancer cell-surface sialylation are not well characterized, specifically in bona fide human disease tissue. Metabolic an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Angew Chem Int Ed Engl
Hauptverfasser: Spiciarich, David R., Nolley, Rosalie, Maund, Sophia L., Purcell, Sean C., Herschel, Jason, Iavarone, Anthony T., Peehl, Donna M., Bertozzi, Carolyn R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675001/
https://ncbi.nlm.nih.gov/pubmed/28649697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201701424
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