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Isotope-targeted glycoproteomics (IsoTaG): a mass-independent platform for intact N- and O-glycopeptide discovery and analysis

Protein glycosylation is a heterogeneous post-translational modification (PTM) that plays an essential role in biological regulation. However, the diversity found in glycoproteins has undermined efforts to describe the intact glycoproteome via mass spectrometry (MS). We present IsoTaG, a mass-indepe...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Methods
Prif Awduron: Woo, Christina M, Iavarone, Anthony T, Spiciarich, David R, Palaniappan, Krishnan K, Bertozzi, Carolyn R
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599779/
https://ncbi.nlm.nih.gov/pubmed/25894945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3366
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