Isotope-targeted glycoproteomics (IsoTaG): a mass-independent platform for intact N- and O-glycopeptide discovery and analysis

Protein glycosylation is a heterogeneous post-translational modification (PTM) that plays an essential role in biological regulation. However, the diversity found in glycoproteins has undermined efforts to describe the intact glycoproteome via mass spectrometry (MS). We present IsoTaG, a mass-indepe...

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Vydáno v:Nat Methods
Hlavní autoři: Woo, Christina M, Iavarone, Anthony T, Spiciarich, David R, Palaniappan, Krishnan K, Bertozzi, Carolyn R
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599779/
https://ncbi.nlm.nih.gov/pubmed/25894945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3366
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