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Isotope-targeted glycoproteomics (IsoTaG): a mass-independent platform for intact N- and O-glycopeptide discovery and analysis

Protein glycosylation is a heterogeneous post-translational modification (PTM) that plays an essential role in biological regulation. However, the diversity found in glycoproteins has undermined efforts to describe the intact glycoproteome via mass spectrometry (MS). We present IsoTaG, a mass-indepe...

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Библиографические подробности
Опубликовано в: :Nat Methods
Главные авторы: Woo, Christina M, Iavarone, Anthony T, Spiciarich, David R, Palaniappan, Krishnan K, Bertozzi, Carolyn R
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599779/
https://ncbi.nlm.nih.gov/pubmed/25894945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3366
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