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Effects of Histone Deacetylase Inhibitor Panobinostat (LBH589) on Bone Marrow Mononuclear Cells of Relapsed or Refractory Multiple Myeloma Patients and Its Mechanisms

BACKGROUND: The aim of this study was to explore the impact of LBH589 alone or in combination with proteasome inhibitor bortezomib on multiple myeloma (MM) cell proliferation and its mechanism. MATERIAL/METHODS: MM cell line U266 and RRMM-BMMNC were treated with different concentrations of LBH589 al...

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Publicado en:Med Sci Monit
Main Authors: Ma, Yanping, Liu, Wenhua, Zhang, Ling, Jia, Gu
Formato: Artigo
Idioma:Inglês
Publicado: International Scientific Literature, Inc. 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674922/
https://ncbi.nlm.nih.gov/pubmed/29080899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.904232
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