Cancer-associated fibroblasts lead tumor invasion through integrin-β3–dependent fibronectin assembly

Cancer-associated fibroblasts (CAFs) are the most abundant cells of the tumor stroma. Their capacity to contract the matrix and induce invasion of cancer cells has been well documented. However, it is not clear whether CAFs remodel the matrix by other means, such as degradation, matrix deposition, o...

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Bibliografische gegevens
Gepubliceerd in:J Cell Biol
Hoofdauteurs: Attieh, Youmna, Clark, Andrew G., Grass, Carina, Richon, Sophie, Pocard, Marc, Mariani, Pascale, Elkhatib, Nadia, Betz, Timo, Gurchenkov, Basile, Vignjevic, Danijela Matic
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2017
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674886/
https://ncbi.nlm.nih.gov/pubmed/28931556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201702033
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