Cancer-associated fibroblasts lead tumor invasion through integrin-β3–dependent fibronectin assembly

Cancer-associated fibroblasts (CAFs) are the most abundant cells of the tumor stroma. Their capacity to contract the matrix and induce invasion of cancer cells has been well documented. However, it is not clear whether CAFs remodel the matrix by other means, such as degradation, matrix deposition, o...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Attieh, Youmna, Clark, Andrew G., Grass, Carina, Richon, Sophie, Pocard, Marc, Mariani, Pascale, Elkhatib, Nadia, Betz, Timo, Gurchenkov, Basile, Vignjevic, Danijela Matic
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674886/
https://ncbi.nlm.nih.gov/pubmed/28931556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201702033
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