Cancer-associated fibroblasts lead tumor invasion through integrin-β3–dependent fibronectin assembly

Cancer-associated fibroblasts (CAFs) are the most abundant cells of the tumor stroma. Their capacity to contract the matrix and induce invasion of cancer cells has been well documented. However, it is not clear whether CAFs remodel the matrix by other means, such as degradation, matrix deposition, o...

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Bibliografiske detaljer
Udgivet i:J Cell Biol
Main Authors: Attieh, Youmna, Clark, Andrew G., Grass, Carina, Richon, Sophie, Pocard, Marc, Mariani, Pascale, Elkhatib, Nadia, Betz, Timo, Gurchenkov, Basile, Vignjevic, Danijela Matic
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2017
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674886/
https://ncbi.nlm.nih.gov/pubmed/28931556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201702033
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