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A new biomimetic assay reveals the temporal role of matrix stiffening in cancer cell invasion

Tumor initiation and growth is associated with significant changes in the surrounding tissue. During carcinoma progression, a global stiffening of the extracellular matrix is observed and is interpreted as a signature of aggressive invasive tumors. However, it is still unknown whether this increase...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Staneva, Ralitza, Burla, Federica, Koenderink, Gijsje H., Descroix, Stéphanie, Vignjevic, Danijela Matic, Attieh, Youmna, Verhulsel, Marine
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6333180/
https://ncbi.nlm.nih.gov/pubmed/30303750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-01-0068
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