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Cells Actively Stiffen Fibrin Networks by Generating Contractile Stress

During wound healing and angiogenesis, fibrin serves as a provisional extracellular matrix. We use a model system of fibroblasts embedded in fibrin gels to study how cell-mediated contraction may influence the macroscopic mechanical properties of their extracellular matrix during such processes. We...

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Autors principals: Jansen, Karin A., Bacabac, Rommel G., Piechocka, Izabela K., Koenderink, Gijsje H.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838739/
https://ncbi.nlm.nih.gov/pubmed/24268136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.10.008
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