Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer’s disease

BACKGROUND: Oligodendrocytes (OLs) and myelin are critical for normal brain function and have been implicated in neurodegeneration. Several lines of evidence including neuroimaging and neuropathological data suggest that Alzheimer’s disease (AD) may be associated with dysmyelination and a breakdown...

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Detalhes bibliográficos
Publicado no:Mol Neurodegener
Main Authors: McKenzie, Andrew T., Moyon, Sarah, Wang, Minghui, Katsyv, Igor, Song, Won-Min, Zhou, Xianxiao, Dammer, Eric B., Duong, Duc M., Aaker, Joshua, Zhao, Yongzhong, Beckmann, Noam, Wang, Pei, Zhu, Jun, Lah, James J., Seyfried, Nicholas T., Levey, Allan I., Katsel, Pavel, Haroutunian, Vahram, Schadt, Eric E., Popko, Brian, Casaccia, Patrizia, Zhang, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674813/
https://ncbi.nlm.nih.gov/pubmed/29110684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-017-0219-3
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