Loss of C/EBPδ enhances IR-induced cell death by promoting oxidative stress and mitochondrial dysfunction

Exposure of cells to ionizing radiation (IR) generates reactive oxygen species (ROS). This results in increased oxidative stress and DNA double strand breaks (DSBs) which are the two underlying mechanisms by which IR causes cell/tissue injury. Cells that are deficient or impaired in the cellular ant...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Banerjee, Sudip, Aykin-Burns, Nukhet, Krager, Kimberly J., Shah, Sumit K., Melnyk, Stepan B., Hauer-Jensen, Martin, Pawar, Snehalata A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673253/
https://ncbi.nlm.nih.gov/pubmed/27554969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2016.08.022
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados