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Mutations that impair Eyes absent tyrosine phosphatase activity in vitro reduce robustness of retinal determination gene network output in Drosophila

A limited collection of signaling networks and transcriptional effectors directs the full spectrum of cellular behaviors that comprise development. One mechanism to diversify regulatory potential is to combine multiple biochemical activities into the same protein. Exemplifying this principle of modu...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Davis, Trevor L., Hoi, Charlene S. L., Rebay, Ilaria
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673202/
https://ncbi.nlm.nih.gov/pubmed/29108015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187546
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