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Mutations that impair Eyes absent tyrosine phosphatase activity in vitro reduce robustness of retinal determination gene network output in Drosophila

A limited collection of signaling networks and transcriptional effectors directs the full spectrum of cellular behaviors that comprise development. One mechanism to diversify regulatory potential is to combine multiple biochemical activities into the same protein. Exemplifying this principle of modu...

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Pubblicato in:PLoS One
Autori principali: Davis, Trevor L., Hoi, Charlene S. L., Rebay, Ilaria
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673202/
https://ncbi.nlm.nih.gov/pubmed/29108015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187546
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