Population pharmacokinetics of moxifloxacin and its concentration–QT interval relationship modeling in Chinese healthy volunteers

Moxifloxacin (MX) is an 8-methoxyquinolone antimicrobial drug, which is often used as a positive control in thorough QT (TQT) studies. In the present study we established the population pharmacokinetics model of MX and the relationship of MX concentrations with the QT and various corrected QT (QTc)...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Acta Pharmacol Sin
Asıl Yazarlar: Xu, Feng-yan, Huang, Ji-han, He, Ying-chun, Liang, Li-yu, Li, Lu-jin, Yang, Juan, Yin, Fang, Xu, Ling, Zheng, Qing-shan, Wang, Kun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2017
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5672076/
https://ncbi.nlm.nih.gov/pubmed/28713157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.76
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