Population pharmacokinetics of moxifloxacin and its concentration–QT interval relationship modeling in Chinese healthy volunteers

Moxifloxacin (MX) is an 8-methoxyquinolone antimicrobial drug, which is often used as a positive control in thorough QT (TQT) studies. In the present study we established the population pharmacokinetics model of MX and the relationship of MX concentrations with the QT and various corrected QT (QTc)...

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Bibliografski detalji
Izdano u:Acta Pharmacol Sin
Glavni autori: Xu, Feng-yan, Huang, Ji-han, He, Ying-chun, Liang, Li-yu, Li, Lu-jin, Yang, Juan, Yin, Fang, Xu, Ling, Zheng, Qing-shan, Wang, Kun
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
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Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5672076/
https://ncbi.nlm.nih.gov/pubmed/28713157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.76
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