Effects of Bardoxolone Methyl on QT Interval in Healthy Volunteers

BACKGROUND: Bardoxolone methyl has been shown to increase eGFR in several clinical trials, including a phase 3 trial in patients with type 2 diabetes and stage 4 CKD (BEACON), which was terminated early due to an increase in heart failure events in bardoxolone methyl-treated patients. A separate, “t...

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Udgivet i:Cardiorenal Med
Main Authors: Chin, Melanie P., Rich, Shannon, Goldsberry, Angie, O'Grady, Megan, Meyer, Colin J.
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger AG 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6751422/
https://ncbi.nlm.nih.gov/pubmed/31158840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000500736
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