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Direct observation of conformational population shifts in crystalline human hemoglobin

Although X-ray crystallography is the most commonly used technique for studying the molecular structure of proteins, it is not generally able to monitor the dynamic changes or global domain motions that often underlie allostery. These motions often prevent crystal growth or reduce crystal order. We...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Shibayama, Naoya, Ohki, Mio, Tame, Jeremy R. H., Park, Sam-Yong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5672048/
https://ncbi.nlm.nih.gov/pubmed/28931607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.781146
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