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Direct observation of conformational population shifts in crystalline human hemoglobin
Although X-ray crystallography is the most commonly used technique for studying the molecular structure of proteins, it is not generally able to monitor the dynamic changes or global domain motions that often underlie allostery. These motions often prevent crystal growth or reduce crystal order. We...
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| Udgivet i: | J Biol Chem |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5672048/ https://ncbi.nlm.nih.gov/pubmed/28931607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.781146 |
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