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Selective and Irreversible Induction of Necroptotic Cell Death in Lung Tumorspheres by Short-Term Exposure to Verapamil in Combination with Sorafenib

The presence of highly resistant cancer cells and the toxicity to normal cells are key factors that limit chemotherapy. Here, we used two models of highly resistant lung cancer cells: (1) adherent cells growing under prolonged periods of serum starvation (PPSS) and (2) cells growing as floating tumo...

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Détails bibliographiques
Publié dans:Stem Cells Int
Auteurs principaux: Yakisich, Juan Sebastian, Kulkarni, Yogesh, Azad, Neelam, Iyer, Anand Krishnan V.
Format: Artigo
Langue:Inglês
Publié: Hindawi 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5671752/
https://ncbi.nlm.nih.gov/pubmed/29201061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/5987015
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