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Selective and Irreversible Induction of Necroptotic Cell Death in Lung Tumorspheres by Short-Term Exposure to Verapamil in Combination with Sorafenib

The presence of highly resistant cancer cells and the toxicity to normal cells are key factors that limit chemotherapy. Here, we used two models of highly resistant lung cancer cells: (1) adherent cells growing under prolonged periods of serum starvation (PPSS) and (2) cells growing as floating tumo...

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Detalhes bibliográficos
Main Authors: Juan Sebastian Yakisich, Yogesh Kulkarni, Neelam Azad, Anand Krishnan V. Iyer
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Limited 2017-01-01
Colecção:Stem Cells International
Acesso em linha:http://dx.doi.org/10.1155/2017/5987015
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