Formation of Tumorspheres with Increased Stemness without External Mitogens in a Lung Cancer Model

Like with most solid tumors, the presence of a subpopulation of cancer stem cells (CSCs) or cancer stem-like cells (CS-LCs) has been associated with chemoresistance and tumor relapse in lung cancer cells. In the absence of serum, CSCs/CS-LCs have the ability to grow as lung tumorspheres (LTSs), and...

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Опубликовано в: :Stem Cells Int
Главные авторы: Yakisich, Juan Sebastian, Azad, Neelam, Venkatadri, Rajkumar, Kulkarni, Yogesh, Wright, Clayton, Kaushik, Vivek, Iyer, Anand Krishnan V.
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Publishing Corporation 2016
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736427/
https://ncbi.nlm.nih.gov/pubmed/26880969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/5603135
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