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Mutational signatures reveal the dynamic interplay of risk factors and cellular processes during liver tumorigenesis

Genomic alterations driving tumorigenesis result from the interaction of environmental exposures and endogenous cellular processes. With a diversity of risk factors, liver cancer is an ideal model to study these interactions. Here, we analyze the whole genomes of 44 new and 264 published liver cance...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Letouzé, Eric, Shinde, Jayendra, Renault, Victor, Couchy, Gabrielle, Blanc, Jean-Frédéric, Tubacher, Emmanuel, Bayard, Quentin, Bacq, Delphine, Meyer, Vincent, Semhoun, Jérémy, Bioulac-Sage, Paulette, Prévôt, Sophie, Azoulay, Daniel, Paradis, Valérie, Imbeaud, Sandrine, Deleuze, Jean-François, Zucman-Rossi, Jessica
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5670220/
https://ncbi.nlm.nih.gov/pubmed/29101368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01358-x
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