Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours

Inflammatory hepatocellular adenomas (IHCA) are benign liver tumours defined by the presence of inflammatory infiltrates and by the elevated expression of inflammatory proteins in tumour hepatocytes1,2. Here we show a striking activation of the IL6 signalling pathway in this tumour type, and sequenc...

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Autores principales: Rebouissou, Sandra, Amessou, Mohamed, Couchy, Gabrielle, Poussin, Karine, Imbeaud, Sandrine, Pilati, Camilla, Izard, Tina, Balabaud, Charles, Bioulac-Sage, Paulette, Zucman-Rossi, Jessica
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695248/
https://ncbi.nlm.nih.gov/pubmed/19020503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07475
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