Somatic mutations activating STAT3 in human inflammatory hepatocellular adenomas

Inflammatory hepatocellular adenomas (IHCAs) are benign liver tumors. 60% of these tumors have IL-6 signal transducer (IL6ST; gp130) mutations that activate interleukin 6 (IL-6) signaling. Here, we report that 12% of IHCA subsets lacking IL6ST mutations harbor somatic signal transducer and activator...

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Autors principals: Pilati, Camilla, Amessou, Mohamed, Bihl, Michel P., Balabaud, Charles, Van Nhieu, Jeanne Tran, Paradis, Valérie, Nault, Jean Charles, Izard, Tina, Bioulac-Sage, Paulette, Couchy, Gabrielle, Poussin, Karine, Zucman-Rossi, Jessica
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2011
Matèries:
Brief Definitive Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135371/
https://ncbi.nlm.nih.gov/pubmed/21690253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20110283
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