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T cells upon activation promote endothelin 1 production in monocytes via IFN-γ and TNF-α
Endothelin 1 (ET-1), mainly produced from vascular endothelial cells, induces vasoconstriction in physiological conditions. The endothelin receptor antagonist is among the most effective agents for pulmonary hypertension. However, little is known about the production source of ET-1 in inflammation a...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5670167/ https://ncbi.nlm.nih.gov/pubmed/29101349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14202-5 |
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