BDNF/trkB Induction of Calcium Transients through Ca(v)2.2 Calcium Channels in Motoneurons Corresponds to F-actin Assembly and Growth Cone Formation on β2-Chain Laminin (221)

Spontaneous Ca(2+) transients and actin dynamics in primary motoneurons correspond to cellular differentiation such as axon elongation and growth cone formation. Brain-derived neurotrophic factor (BDNF) and its receptor trkB support both motoneuron survival and synaptic differentiation. However, in...

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Veröffentlicht in:Front Mol Neurosci
Hauptverfasser: Dombert, Benjamin, Balk, Stefanie, Lüningschrör, Patrick, Moradi, Mehri, Sivadasan, Rajeeve, Saal-Bauernschubert, Lena, Jablonka, Sibylle
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5670157/
https://ncbi.nlm.nih.gov/pubmed/29163025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00346
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