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Inhibition of Aurora Kinase A Induces Necroptosis in Pancreatic Carcinoma
BACKGROUND & AIMS: Induction of non-apoptotic cell death could be an approach to eliminate apoptosis-resistant tumors. We investigated necroptosis-based therapies in mouse models of pancreatic ductal adenocarcinoma cancer (PDAC). METHODS: We screened 273 commercially available kinase inhibitors...
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| Gepubliceerd in: | Gastroenterology |
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| Hoofdauteurs: | , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5670014/ https://ncbi.nlm.nih.gov/pubmed/28764929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2017.07.036 |
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