Molecular chaperones in the acquisition of cancer cell chemoresistance with mutated TP53 and MDM2 up-regulation

Utilizing the TCGA PANCAN12 dataset we discovered that cancer patients with mutations in TP53 tumor suppressor and overexpression of MDM2 oncogene exhibited decreased survival post treatment. Interestingly, in the case of breast cancer patients, this phenomenon correlated with high expression level...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Tracz-Gaszewska, Zuzanna, Klimczak, Marta, Biecek, Przemyslaw, Herok, Marcin, Kosinski, Marcin, Olszewski, Maciej B., Czerwińska, Patrycja, Wiech, Milena, Wiznerowicz, Maciej, Zylicz, Alicja, Zylicz, Maciej, Wawrzynow, Bartosz
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669876/
https://ncbi.nlm.nih.gov/pubmed/29137250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18899
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker