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CDK9-dependent RNA polymerase II pausing controls transcription initiation
Gene transcription can be activated by decreasing the duration of RNA polymerase II pausing in the promoter-proximal region, but how this is achieved remains unclear. Here we use a ‘multi-omics’ approach to demonstrate that the duration of polymerase pausing generally limits the productive frequency...
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| Pubblicato in: | eLife |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
eLife Sciences Publications, Ltd
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5669633/ https://ncbi.nlm.nih.gov/pubmed/28994650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.29736 |
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