Treg depletion potentiates checkpoint inhibition in claudin-low breast cancer

Claudin-low breast cancer is an aggressive subtype that confers poor prognosis and is found largely within the clinical triple-negative group of breast cancer patients. Here, we have shown that intrinsic and immune cell gene signatures distinguish the claudin-low subtype clinically as well as in mou...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Taylor, Nicholas A., Vick, Sarah C., Iglesia, Michael D., Brickey, W. June, Midkiff, Bentley R., McKinnon, Karen P., Reisdorf, Shannon, Anders, Carey K., Carey, Lisa A., Parker, Joel S., Perou, Charles M., Vincent, Benjamin G., Serody, Jonathan S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669567/
https://ncbi.nlm.nih.gov/pubmed/28825599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI90499
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