Treg depletion potentiates checkpoint inhibition in claudin-low breast cancer

Claudin-low breast cancer is an aggressive subtype that confers poor prognosis and is found largely within the clinical triple-negative group of breast cancer patients. Here, we have shown that intrinsic and immune cell gene signatures distinguish the claudin-low subtype clinically as well as in mou...

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Vydáno v:J Clin Invest
Hlavní autoři: Taylor, Nicholas A., Vick, Sarah C., Iglesia, Michael D., Brickey, W. June, Midkiff, Bentley R., McKinnon, Karen P., Reisdorf, Shannon, Anders, Carey K., Carey, Lisa A., Parker, Joel S., Perou, Charles M., Vincent, Benjamin G., Serody, Jonathan S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669567/
https://ncbi.nlm.nih.gov/pubmed/28825599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI90499
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