Epiregulin and EGFR interactions are involved in pain processing

The EGFR belongs to the well-studied ErbB family of receptor tyrosine kinases. EGFR is activated by numerous endogenous ligands that promote cellular growth, proliferation, and tissue regeneration. In the present study, we have demonstrated a role for EGFR and its natural ligand, epiregulin (EREG),...

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Bibliografski detalji
Izdano u:J Clin Invest
Glavni autori: Martin, Loren J., Smith, Shad B., Khoutorsky, Arkady, Magnussen, Claire A., Samoshkin, Alexander, Sorge, Robert E., Cho, Chulmin, Yosefpour, Noosha, Sivaselvachandran, Sivaani, Tohyama, Sarasa, Cole, Tiffany, Khuong, Thang M., Mir, Ellen, Gibson, Dustin G., Wieskopf, Jeffrey S., Sotocinal, Susana G., Austin, Jean Sebastien, Meloto, Carolina B., Gitt, Joseph H., Gkogkas, Christos, Sonenberg, Nahum, Greenspan, Joel D., Fillingim, Roger B., Ohrbach, Richard, Slade, Gary D., Knott, Charles, Dubner, Ronald, Nackley, Andrea G., Ribeiro-da-Silva, Alfredo, Neely, G. Gregory, Maixner, William, Zaykin, Dmitri V., Mogil, Jeffrey S., Diatchenko, Luda
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2017
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669538/
https://ncbi.nlm.nih.gov/pubmed/28783046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI87406
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