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Genetic modifiers of muscular dystrophy act on sarcolemmal resealing and recovery from injury
Genetic disruption of the dystrophin complex produces muscular dystrophy characterized by a fragile muscle plasma membrane leading to excessive muscle degeneration. Two genetic modifiers of Duchenne Muscular Dystrophy implicate the transforming growth factor β (TGFβ) pathway, osteopontin encoded by...
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| Veröffentlicht in: | PLoS Genet |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5669489/ https://ncbi.nlm.nih.gov/pubmed/29065150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007070 |
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