Genetic modifiers of muscular dystrophy act on sarcolemmal resealing and recovery from injury

Genetic disruption of the dystrophin complex produces muscular dystrophy characterized by a fragile muscle plasma membrane leading to excessive muscle degeneration. Two genetic modifiers of Duchenne Muscular Dystrophy implicate the transforming growth factor β (TGFβ) pathway, osteopontin encoded by...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Quattrocelli, Mattia, Capote, Joanna, Ohiri, Joyce C., Warner, James L., Vo, Andy H., Earley, Judy U., Hadhazy, Michele, Demonbreun, Alexis R., Spencer, Melissa J., McNally, Elizabeth M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669489/
https://ncbi.nlm.nih.gov/pubmed/29065150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007070
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