Nilotinib-induced vasculopathy: identification of vascular endothelial cells as a primary target site

The BCR/ABL1 inhibitor Nilotinib is increasingly used to treat patients with chronic myeloid leukemia (CML). Although otherwise well-tolerated, Nilotinib has been associated with the occurrence of progressive arterial occlusive disease (AOD). Our objective was to determine the exact frequency of AOD...

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Vydáno v:Leukemia
Hlavní autoři: Hadzijusufovic, Emir, Albrecht-Schgoer, Karin, Huber, Kilian, Hoermann, Gregor, Grebien, Florian, Eisenwort, Gregor, Schgoer, Wilfried, Herndlhofer, Susanne, Kaun, Christoph, Theurl, Markus, Sperr, Wolfgang R., Rix, Uwe, Sadovnik, Irina, Jilma, Bernd, Schernthaner, Gerit H., Wojta, Johann, Wolf, Dominik, Superti-Furga, Giulio, Kirchmair, Rudolf, Valent, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669463/
https://ncbi.nlm.nih.gov/pubmed/28757617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2017.245
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