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Investigation of FoxO3 dynamics during erythroblast development in β-thalassemia major
The FoxO3 transcription factor is a key regulator of oxidative stress and erythroid maturation during erythropoiesis. In this study, we explored the involvement of FoxO3 in severe β-thalassemia. Using primary CD34(+) hematopoietic progenitor cells from patients with β-thalassemia major, we successfu...
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| Publicado en: | PLoS One |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5669432/ https://ncbi.nlm.nih.gov/pubmed/29099866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187610 |
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