Enhancement of β‐Globin Gene Expression in Thalassemic IVS2‐654 Induced Pluripotent Stem Cell‐Derived Erythroid Cells by Modified U7 snRNA

The therapeutic use of patient‐specific induced pluripotent stem cells (iPSCs) is emerging as a potential treatment of β‐thalassemia. Ideally, patient‐specific iPSCs would be genetically corrected by various approaches to treat β‐thalassemia including lentiviral gene transfer, lentivirus‐delivered s...

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Vydáno v:Stem Cells Transl Med
Hlavní autoři: Phanthong, Phetcharat, Borwornpinyo, Suparerk, Kitiyanant, Narisorn, Jearawiriyapaisarn, Natee, Nuntakarn, Lalana, Saetan, Jirawat, Nualkaew, Tiwaporn, Sa‐ngiamsuntorn, Khanit, Anurathapan, Usanarat, Dinnyes, Andras, Kitiyanant, Yindee, Hongeng, Suradej
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
Translational Research Articles and Reviews
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442829/
https://ncbi.nlm.nih.gov/pubmed/28213976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.16-0121
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