Upregulation of CYP 450s expression of immortalized hepatocyte-like cells derived from mesenchymal stem cells by enzyme inducers

BACKGROUND: The strenuous procurement of cultured human hepatocytes and their short lives have constrained the cell culture model of cytochrome P450 (CYP450) induction, xenobiotic biotransformation, and hepatotoxicity. The development of continuous non-tumorous cell line steadily containing hepatocy...

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Main Authors: Sa-ngiamsuntorn, Khanit, Wongkajornsilp, Adisak, Kasetsinsombat, Kanda, Duangsa-ard, Sunisa, Nuntakarn, Lalana, Borwornpinyo, Suparerk, Akarasereenont, Pravit, Limsrichamrern, Somchai, Hongeng, Suradej
格式: Artigo
語言:Inglês
出版: BioMed Central 2011
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198927/
https://ncbi.nlm.nih.gov/pubmed/21961524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-11-89
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