Upregulation of CYP 450s expression of immortalized hepatocyte-like cells derived from mesenchymal stem cells by enzyme inducers

BACKGROUND: The strenuous procurement of cultured human hepatocytes and their short lives have constrained the cell culture model of cytochrome P450 (CYP450) induction, xenobiotic biotransformation, and hepatotoxicity. The development of continuous non-tumorous cell line steadily containing hepatocy...

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Главные авторы: Sa-ngiamsuntorn, Khanit, Wongkajornsilp, Adisak, Kasetsinsombat, Kanda, Duangsa-ard, Sunisa, Nuntakarn, Lalana, Borwornpinyo, Suparerk, Akarasereenont, Pravit, Limsrichamrern, Somchai, Hongeng, Suradej
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2011
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198927/
https://ncbi.nlm.nih.gov/pubmed/21961524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-11-89
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