Upregulation of CYP 450s expression of immortalized hepatocyte-like cells derived from mesenchymal stem cells by enzyme inducers

BACKGROUND: The strenuous procurement of cultured human hepatocytes and their short lives have constrained the cell culture model of cytochrome P450 (CYP450) induction, xenobiotic biotransformation, and hepatotoxicity. The development of continuous non-tumorous cell line steadily containing hepatocy...

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Autores principales: Sa-ngiamsuntorn, Khanit, Wongkajornsilp, Adisak, Kasetsinsombat, Kanda, Duangsa-ard, Sunisa, Nuntakarn, Lalana, Borwornpinyo, Suparerk, Akarasereenont, Pravit, Limsrichamrern, Somchai, Hongeng, Suradej
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198927/
https://ncbi.nlm.nih.gov/pubmed/21961524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-11-89
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